Search results for "Albizia adianthifolia"

showing 4 items of 4 documents

Two new biologically active triterpenoidal saponins acylated with salicylic acid from Albizia adianthifolia

2003

International audience; Two new oleanane-type triterpene saponins, adianthifoliosides A (1) and B (2), were isolated from a 95% ethanolic extract of roots of Albizia adianthifolia. Their structures were elucidated mainly by using a combination of 600 MHz 1D and 2D NMR techniques (COSY, NOESY, TOCSY, HSQC, and HMBC) and by FABMS and HRESIMS. Compounds 1 and 2 were characterized as glycosides of acacic acid acylated by an o-hydroxybenzoyl unit. The crude saponin mixture (CSM), compounds 1 and 2 together with 3 and 4 (prosapogenins obtained from the mild alkaline hydrolysate of the CSM), were evaluated for immunomodulatory activity on the Jurkat T cell line and for hemolytic property against s…

ErythrocytesStereochemistrySaponinPharmaceutical ScienceAlbizziaPharmacognosy01 natural sciencesHemolysisPlant Roots[ CHIM ] Chemical SciencesHydrolysateAnalytical Chemistry[ SDV.EE ] Life Sciences [q-bio]/Ecology environmentJurkat CellsTriterpeneAdjuvants ImmunologicDrug DiscoveryAnimalsHumans[CHIM]Chemical SciencesOleanolic AcidNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classification[SDV.EE]Life Sciences [q-bio]/Ecology environmentPlants MedicinalSheepbiologyDose-Response Relationship DrugMolecular Structure010405 organic chemistryOrganic ChemistryGlycosideBiological activityAcetylationSaponinsbiology.organism_classificationAntineoplastic Agents PhytogenicTerpenoidTriterpenes0104 chemical sciences010404 medicinal & biomolecular chemistryCote d'IvoireComplementary and alternative medicinechemistryMolecular MedicineSalicylic AcidAlbizia adianthifolia
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New Triterpenoidal Saponins Acylated with Monoterpenic Acid fromAlbizia adianthifolia

2004

Four new triterpenoidal saponins acylated with monoterpenic acid, i.e., adianthifoliosides C, D, E, and F (1–4), besides the two known julibroside III and the monodesmonoterpenyl elliptoside A, were isolated from the roots of Albizia adianthifolia. Their structures were elucidated on the basis of extensive 1D- and 2D-NMR studies and mass spectrometry as 3-O-{O-α-L-arabinopyranosyl-(12)-O-β-d-fucopyranosyl-(16)-O-[β-d-glucopyranosyl-(12)]-β-d-glucopyranosyl}-21-O-{(2E,6S)-6-{{4-O-[(2E,6S)-2,6-dimethyl-6-(β-D-quinovopyranosyloxy)octa-2,7-dienoyl]-β-d-quinovopyranosyl}oxy}-2-(hydroxymethyl)-6-methylocta-2,7-dienoyl}acacic acid 28-{O-α-L-arabinofuranosyl-(14)-O-[β-d-glucopyranosyl-(13)]-O-α-L-r…

Inorganic Chemistrychemistry.chemical_compoundbiologyStereochemistryChemistryOrganic ChemistryDrug DiscoveryHydroxymethylPhysical and Theoretical Chemistrybiology.organism_classificationBiochemistryCatalysisAlbizia adianthifoliaHelvetica Chimica Acta
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Induction of apoptosis in a leukemia cell line by triterpene saponins from Albizia adianthifolia

2004

Abstract Triterpenoid saponins, which are present in plants and some marine animals, exert various important pharmacological effects. The present study examines the effects of adianthifoliosides A, B, and D (AdA, AdB, and AdD) together with two prosapogenins (Pro1 and Pro2) obtained from Albizia adianthifolia (Mimosaceae) on human leukemia T-cells (Jurkat cells) and on splenocytes. AdA, AdB, and AdD were found to exhibit a cytotoxic effect on Jurkat cells, whereas the prosapogenins were found to exert a lymphoproliferative effect on this cell type. Furthermore, all tested compounds were found to exert a synergistic lymphoproliferative activity with concanavalin A (ConA) on splenocytes. The …

T-LymphocytesClinical BiochemistryPharmaceutical ScienceAlbizziaApoptosisHemolysisBiochemistryJurkat cellsCell LineJurkat Cellschemistry.chemical_compoundDrug DiscoveryTumor Cells CulturedHumansCytotoxic T cellPropidium iodideOleanolic AcidCytotoxicityMolecular BiologyPlants MedicinalDose-Response Relationship DrugbiologyChemistryOrganic ChemistryBiological activitySaponinsbiology.organism_classificationAntineoplastic Agents PhytogenicTriterpenesBiochemistryConcanavalin ACell culturebiology.proteinMolecular MedicineAlbizia adianthifoliaBioorganic & Medicinal Chemistry
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Saponin with antibacterial activity from the roots of Albizia adianthifolia

2019

AbstractAn unprecedented saponin is being reported herein together with five known compounds from the methanol extract of the roots of Albizia adianthifolia. The metabolites were obtained over repe...

chemistry.chemical_classificationbiologyTraditional medicine010405 organic chemistryChemistryOrganic ChemistrySaponinPlant Sciencebiology.organism_classification01 natural sciencesBiochemistry0104 chemical sciencesAnalytical Chemistry010404 medicinal & biomolecular chemistryAntibacterial activityAlbizia adianthifoliaNatural Product Research
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